https://graemekinglab.com/publications daily 0.75 2026-01-23 https://images.squarespace-cdn.com/content/v1/5ce435d6bea1ed00016ba287/1558964652247-5MWXNMFZVOPGE4TY6U2Q/MHeiderich_ReflexionenZwei-05-copy.jpg PUBLICATIONS https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/5fef56bd-f7bb-4422-9d51-812939232031/36.jpg PUBLICATIONS D. Spakman, A.S. Biebricher, A.H. Bizard, I.D. Hickson, E.J.G. Peterman,* G.J.L. Wuite,* and G.A. King* Proceedings of the National Academy of Sciences, 123, e2406949123 (2026) * co-corresponding authors https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/13ab8da3-b5d1-4705-b123-2782aa5df9ae/cover.tif.jpg PUBLICATIONS M.D. Newton, M. Losito, Q.M. Smith, N. Parnandi, B.J. Taylor, P. Akcakaya, M. Maresca, P. van Eijk, S.H. Reed, S.J. Boulton, G.A. King,* M.E. Cuomo,* D.S. Rueda* Molecular Cell, 83, 3533–3545 (2023) - front cover * co-corresponding authors https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/431ea32d-0ccf-4b78-b5bd-6fedeb03aa2d/34.jpg PUBLICATIONS D. Spakman, T.V.M. Clement, A.S. Biebricher, G.A. King, M.I. Singh, I.D. Hickson, E.J.G. Peterman and G.J.L. Wuite Nature Communications, 13, 7277 (2022) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/5d907c00-52a1-45c4-92b5-bc478286d389/ODS+detailed.jpg PUBLICATIONS G.A. King,* D. Spakman, E.J.G. Peterman* and G.J.L. Wuite* Optical Tweezers: Methods in Molecular Biology, 2478, 243-272 (2022) * co-corresponding authors https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/3379c1b6-af68-4fb1-8b35-1a079b886d22/32.jpg PUBLICATIONS J.A.M. Bakx,# A.S. Biebricher,# G.A. King,# P. Christodoulis, K. Sarlós, A.H. Bizard, I.D Hickson, G.J.L. Wuite and E.J.G. Peterman Nature Communications, 13, 584 (2022) # joint first authors https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/9aa6f211-e1a7-476b-aab7-cc2a9410d317/31.jpg PUBLICATIONS A.S. Backer, G.A. King, A.S. Biebricher, J.W. Shepherd, A. Noy, M.C. Leake, I. Heller, G.J.L. Wuite and E.J.G. Peterman Journal of Physical Chemistry B, 125, 8351–8361 (2021) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/6dba4b97-89ae-4d90-9203-b45382f5cf37/30-new.jpg PUBLICATIONS D. Spakman, J.A.M. Bakx, A.S. Biebricher, E.J.G. Peterman,* G.J.L. Wuite* and G.A. King,* Nucleic Acids Research, 49, 5470–5492 (2021) * co-corresponding authors https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/ef3ab963-68a4-414c-b94d-0af8235d2eb0/29.jpg PUBLICATIONS D. Spakman, G.A. King,* E.J.G. Peterman* and G.J.L. Wuite,* Scientific Reports, 10, 9903 (2020) * co-corresponding authors https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/188ee126-fd9a-4d75-ac2c-46ebb181094f/28b.jpg PUBLICATIONS G.A. King,* F. Burla, E.J.G. Peterman* and G.J.L. Wuite* Proceedings of the National Academy of Sciences, 116, 26534–26539 (2019) * co-corresponding authors https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/55325788-3460-4879-917a-e2a83f7aad38/27.jpg PUBLICATIONS A.S. Backer, A.S. Biebricher, G.A. King, G.J.L. Wuite, I. Heller and E.J.G. Peterman Science Advances, 5, eaav1083 (2019) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/240480bd-a62e-45bb-822e-d670f9af7b82/26.jpg PUBLICATIONS S.K. Bharti, Y. Wu, J.A. Sommers, I. Khan, L. Bradley, G.A. King, Y. Seol, T. Abe, K. Kobayashi, K. Shin-Ya, H. Kitao, M.S. Wold, D. Branzei, K.C. Neuman and R.M. Brosh, Jr. Nucleic Acids Research, 46, 6238–6256 (2018) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/5a4584bf-6b84-44b2-b252-7aa86dd945d5/25.jpg PUBLICATIONS G.A. King, M.H. Shabestari, K. Taris, A. Pandey, S. Venkatesh, J. Thilagavathi, D. Temiakov, W.H. Roos, C.K. Suzuki and G.J.L. Wuite Nucleic Acids Research, 46, 3633–3642 (2018) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/5e650f47-ae86-4d84-afc3-0acf1a9f6aec/24.jpg PUBLICATIONS G.A. King, A.S. Biebricher, I. Heller, E.J.G. Peterman and G.J.L. Wuite Nano Letters, 18, 2274–2281 (2018) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/eb595d26-db0a-4c0a-b57b-0d567ff4197c/23.jpg PUBLICATIONS I. Brouwer, G.A. King, I. Heller, A.S. Biebricher, E.J.G. Peterman and G.J.L. Wuite Optical Tweezers: Methods in Molecular Biology, 1486, 275 (2017) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/75b22534-712b-4503-a372-5f580e357eb8/22.jpg PUBLICATIONS I. Heller, N. Laurens, D. Vorselen, O.D. Broekmans, A.S. Biebricher, G.A. King, I. Brouwer, G.J.L. Wuite and E.J.G. Peterman Optical Tweezers: Methods in Molecular Biology, 1486, 257, (2017) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/bb0a69df-e604-4d8c-bfce-8064f8a0341f/21.jpg PUBLICATIONS O.D. Broekmans, G.A. King, G.J. Stephens and G.J.L. Wuite Physical Review Letters, 116, 258102 (2016) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/ca326806-80a2-4449-85cc-b8f3c5183efd/20.jpg PUBLICATIONS G.A. King, E.J.G. Peterman and G.J.L. Wuite Nature Communications, 7, 11810 (2016) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/6a243b2b-029b-4239-ade7-5fb677a74ae0/19.jpg PUBLICATIONS I. Heller, T.P. Hoekstra, G.A. King, E.J.G. Peterman and G.J.L. Wuite Chemical Reviews, 114, 3087 (2014) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/f51c6794-8bf3-453b-892e-001a7695ca7d/18.jpg PUBLICATIONS G. A. King and G. J. L. Wuite Nature Chemistry, 6, 13-14 (2014) – News and Views https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/4ff64f33-5db6-4380-943d-fcab86531d23/17.jpg PUBLICATIONS G.A. King, P. Gross, U. Bockelmann, M. Modesti, G.J.L. Wuite and E.J.G. Peterman Proceedings of the National Academy of Sciences, 110, 3589 (2013) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/19a44953-0a01-445d-b973-71eb6e08dafc/16.jpg PUBLICATIONS A.G. Sage, T.A.A. Oliver, G.A. King, D. Murdock, J.N. Harvey and M.N.R. Ashfold Journal of Chemical Physics, 138 164318 (2013) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/85cf0025-1495-4a25-bd3c-bc01681ed893/15.jpg PUBLICATIONS T.A.A. Oliver, G.A. King, D.P. Tew, R.N. Dixon and M.N.R. Ashfold Journal of Physical Chemistry A, 116, 12444 (2012) - Front Cover https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/d028c80f-eafc-469f-90fe-694c2b80a322/14.jpg PUBLICATIONS G.A. King, T.A.A. Oliver, R.N. Dixon and M.N.R. Ashfold Physical Chemistry Chemical Physics, 14, 3338 (2012) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/0401fb69-4e3f-4de4-88cb-ab8960b602d3/13.jpg PUBLICATIONS T.A.A. Oliver, G.A. King and M.N.R. Ashfold Physical Chemistry Chemical Physics, 13, 14646 (2011) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/42474aaa-2f31-416b-9919-3f158d94ea4e/12.jpg PUBLICATIONS T.A.A. Oliver, G.A. King, A.G. Sage and M.N.R. Ashfold Conical Intersections: Theory, Computation and Experiment, 603-633 (2011) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/d948c4df-2679-4f40-9af7-10ebdab97f65/11.jpg PUBLICATIONS M.N.R. Ashfold, G.A. King, M.G.D. Nix and T.A.A. Oliver Handbook of High Resolution Spectroscopy, Wiley 1859 (2011) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/1d0f5737-1754-4a72-97d9-85a02481b3fe/10.jpg PUBLICATIONS G.A. King, T.A.A. Oliver and M.N.R. Ashfold Journal of Chemical Physics, 132, 214307 (2010) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/1927f12b-8ac6-4ab1-b994-a595f041b6e7/9.jpg PUBLICATIONS G.A. King, T.A.A. Oliver, M.G.D. Nix and M.N.R. Ashfold Journal of Chemical Physics 132, 064305 (2010) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/c68eb907-9eeb-4e15-93c3-da83d076b0cf/8.jpg PUBLICATIONS - M.N.R. Ashfold, G.A. King, D. Murdock, M.G.D. Nix, T.A.A. Oliver and A.G. Sage Physical Chemistry Chemical Physics, 12, 1218 (2010) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/1f556739-0fd7-4662-abb2-a85720cdb9c1/7.jpg PUBLICATIONS T.A.A. Oliver, G.A. King and M.N.R. Ashfold Journal of Chemical Physics, 133 194303 (2010) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/f7a3f5df-d724-4b00-a189-39c4a6787a3f/6.jpg PUBLICATIONS T.A.A. Oliver, G.A. King and M.N.R. Ashfold Chemical Science, 1, 89 (2010) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/4858a304-b732-44e8-8a8c-9f5533695704/5.jpg PUBLICATIONS T.A.A. Oliver, G.A. King, M.G.D. Nix and M.N.R. Ashfold Journal of Physical Chemistry A, 114, 1338 (2010) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/bfd3a1d9-4188-478f-99bf-51fbc8516b23/4.jpg PUBLICATIONS G.A. King, T.A.A. Oliver, M.G.D. Nix and M.N.R. Ashfold Journal of Physical Chemistry A, 113, 7984 (2009) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/8c859a3c-8587-4e38-ba6e-714f757f9e8b/3.jpg PUBLICATIONS G.A. King, A.L. Devine, M.G.D. Nix, D.E. Kelly and M.N.R. Ashfold Physical Chemistry Chemical Physics, 10, 6417 (2008) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/560bc399-67db-41ef-965c-4f79d066b158/2.jpg PUBLICATIONS M.N.R. Ashfold, A.L. Devine, R.N. Dixon, G.A. King, M.G.D. Nix and T.A.A. Oliver Proceedings of the National Academy of Sciences, 105, 12701 (2008) https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/27a08990-9296-4362-b881-591a22515e5b/1.jpg PUBLICATIONS L. Rubio-Lago, D. Zaouris, Y. Sofikitis, T.N. Kitsopoulos, F. Wang, X. Yang, B. Cronin, A.L. Devine, G.A. King, M.G.D. Nix and M.N.R. Ashfold Journal of Chemical Physics, 127, 064306 (2007) https://graemekinglab.com/home daily 1.0 2023-11-14 https://graemekinglab.com/research daily 0.75 2023-11-14 https://images.squarespace-cdn.com/content/v1/5ce435d6bea1ed00016ba287/1558964652247-5MWXNMFZVOPGE4TY6U2Q/MHeiderich_ReflexionenZwei-05-copy.jpg RESEARCH https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/87d38fa3-19c0-4cc9-8ad8-2e0278fa0b8b/ODS+new.jpg RESEARCH - Make it stand out Application of optical tweezers and fluorescence imaging to determine the influence of tension and torsional stress on DNA structure. See also PNAS (2013), Nat. Commun. (2016), PNAS (2019) and J. Phys. Chem. B (2021). https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/ae0c8967-eb80-4db2-b510-7f034c725f4b/TFAM+sliding+4.jpg RESEARCH - Make it stand out Fluorescence kymograph showing the sliding of a single TFAM protein on DNA. See also PNAS (2019) and Nucleic Acids Res. (2018). https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/497c134b-a922-4ca7-b46f-571490263190/Topoisomerase+figure3.jpg RESEARCH - Make it stand out Catalytic cycle of Type 1A topoisomerases (upper), and our experimental strategy to measure enzyme-mediated gate opening on single-stranded DNA (lower). See also Nat. Commun. (2022) and Nucleic Acids Res. (2021). https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/f752a027-b6af-4e51-ae4d-ad6dd6dcb452/ODS+detailed.jpg RESEARCH - Make it stand out Schematic showing the principle of Optical DNA Supercoiling: repeated stretch and retract cycles (steps 1-5) allow controlled changes in the DNA linking number. See also PNAS (2019). https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/4fe84fb9-de71-48b0-b35a-021c70529d9d/Briad_3.jpg RESEARCH - Make it stand out Kymograph showing the change in intercalator fluorescence upon sliding one entwined DNA molecule through another. The change in fluorescence can be used to measure the frictional force. See also Nano Lett. (2018). https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/861934c9-e5fa-485a-b282-336c8679e5c9/Sci+rep+new3.jpg RESEARCH - Make it stand out Synthesis of defined arrays of nucleosome positioning sequences, which can be used to generate arrays of nucleosomes for single-molecule studies. See also Sci. Rep. (2020). https://graemekinglab.com/members daily 0.75 2025-11-13 https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/18bed060-098b-4e80-96fe-10a13f2f4d46/Photo_Graeme.jpg MEMBERS https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/a0979424-d533-4001-a62c-3c48680a8b7f/20220306_092710.jpg MEMBERS https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/373522c0-1424-4867-9c76-cdf59294212f/Photo.jpg MEMBERS https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/4d1e2f71-2e75-481e-ab3a-e7c0e99b2c2c/Galaxy.jpeg MEMBERS https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/fd190066-02d6-48f4-9627-2edccd71d1a3/Leo.jpg MEMBERS https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/26af23b8-5dc4-4513-bc1f-363b5b9ad634/Nimit.jpg MEMBERS https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/e4508da7-0d02-4fd8-8c7e-c890a3a671e4/Gabby.JPG MEMBERS https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/5da3c9ee-b59a-4357-b8ff-6d7224e4835b/Lab+Photo.jpg https://graemekinglab.com/contact daily 0.75 2023-11-14 https://images.squarespace-cdn.com/content/v1/5ce435d6bea1ed00016ba287/1558964652247-5MWXNMFZVOPGE4TY6U2Q/MHeiderich_ReflexionenZwei-05-copy.jpg CONTACT https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/c5912475-66ee-4cf7-b7bf-560ba4e9fcf7/UCL.jfif CONTACT - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://graemekinglab.com/graeme daily 0.75 2023-11-14 https://images.squarespace-cdn.com/content/v1/62798502d07d29334cdd8429/6a5981cd-7416-49ca-8e30-af76c346f6d3/Photo_Graeme.jpg